Murine peritoneal neutrophil activation upon tungsten nanoparticles exposure in vivo

Authors

  • E. A. Martinova Russian Medical Academy of the Post-diploma education, 123995, Moscow, 2/1 Barrikadnaya St., e-mail: e.a.martinova@gmail.com
  • V. I. Baranov Russian Medical Academy of the Post-diploma education, 123995, Moscow, 2/1 Barrikadnaya St., e-mail: e.a.martinova@gmail.com

Keywords:

nanoparticles, tungsten carbide, neutrophil activation

Abstract

Two examples of tungsten carbide nanoparticles (d = 15 nm, 50 nm) and tungsten carbide nanoparticles with 8% cobalt (d = 50 nm) have been found to induce the neutrophil activation 3 h and 36 h after intraperitoneal administration in the doses 0,005; 0,025; 0,05; 0,25; 0,5; 1; 2,5 and 5 microgram per 1 gram body weight to FVB mice. Neutrophil activation was calculated based on the CD11b and S100 antigen expression. Effect of nanoparticles is bimodal for all tested examples.

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Published

2014-09-12

Issue

Vol. 58 No. 3 (2014)

Section

Brief Reports

How to Cite

[1]
2014. Murine peritoneal neutrophil activation upon tungsten nanoparticles exposure in vivo. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 58, 3 (Sep. 2014), 73–75.