The influence of hepatocyte growth factor on lipid peroxidation processes in stress

Authors

  • V.I. Korosin Kursk State Medical University, 3, Karla Marksa str., 305004, Kursk, Russia
  • Yu.D. Lyashev Kursk State Medical University, 3, Karla Marksa str., 305004, Kursk, Russia
  • A.V. Solin Kursk State Medical University, 3, Karla Marksa str., 305004, Kursk, Russia

Keywords:

stress, hepatocyte growth factor, lipid peroxidation, antioxidants enzymes

Abstract

The influence of hepatocyte growth factor (HGF) on the activation of lipid peroxidation (LP) and activity of antioxidant enzymes in rat plasma was investigated in immobilization stress. It was established that investigated peptide decreases stress-induced activation of lipid peroxidation manifesting by the decrease of the content of intermediate and final metabolites of LP in plasma. HGF causes the increase of the activity of catalase (enzyme of antioxidant system) also, which decreased under stress influence.

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Published

2013-08-12

Issue

Vol. 57 No. 3 (2013)

Section

Original research

How to Cite

[1]
2013. The influence of hepatocyte growth factor on lipid peroxidation processes in stress. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 57, 3 (Aug. 2013), 62–64.