Characteristic populations of t and в lymphocytes, nk-cell and activation markers in children with myopia depending on the starting level of the immune status

Authors

  • N. V. Khamnagdaeva N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation http://orcid.org/0000-0003-1167-9226
  • L. Y. Semenova N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • S. A. Obrubov N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • J. М. Salmasi N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • G. V. Poryadin N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
  • I. V. Rogozhina Child medical center Office of the president RF, Moscow, Russian Federation

Keywords:

myopia, immunit

Abstract

The purpose: To study the characteristics of populations of T and B lymphocytes, NK- cells and activation markers in children with myopia, depending on the initial level of immune status. Methods. The study involved 30 patients. Determined ophthalmology status and the peripheral blood of patients content determined lymphocytes expressing antigens CD3, CD4, CD8, CD 16, CD56, CD 20, CD 72, CD 38, CD 25, CD 71, HLA-DR, CD 95, CD 54, mIgM, mIgG. Results: there are increase lymphocyte expression of CD20 and ICAM-1 antigens in peripheral blood in patient with myopia, that can be associated with production of free radical generator which is a trans-retinal. Inhibition of the expression of antigens lymphocyte subpopulation of myopia in children with secondary immunodeficiency reflects the involvement of the immune system in the disease process, and apparently not associated with myopia.

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Published

2016-05-27

Issue

Vol. 60 No. 2 (2016)

Section

Original research

How to Cite

[1]
2016. Characteristic populations of t and в lymphocytes, nk-cell and activation markers in children with myopia depending on the starting level of the immune status. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 60, 2 (May 2016), 29–33.

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