Systemic factors of acute pancreatitis advance

Authors

  • G. V. Poryadin Russian National Research Medical University of N.I. Pirogov, Moscow, Rusian Federation
  • A. P. Vlasov Mordovian state university of N. P. Ogaryov, Saransk, , Rusian Federation
  • S. G. Anasskin Medical faculty of Obninsk institute of nuclear power, Obninsk, Rusian Federation
  • T. I. Vlasova Mordovian state university of N. P. Ogaryov, Saransk, , Rusian Federation
  • I. V. Potynova Russian National Research Medical University of N.I. Pirogov, Moscow, Rusian Federation
  • S. A. Turigina Russian National Research Medical University of N.I. Pirogov, Moscow, Rusian Federation

Keywords:

pancreatitis, endotoxicosis, lipid peroxidation, intestines, liver, kidneys

Abstract

In experimental studies the sequence of vitals series lesion is established at various forms of acute experimental pancreatitis (edematous pancreatitis, a pancreatonecrosis). It is shown that one of the first in pathological process involves an intestine, then — a liver, further — kidneys. It is established that at acute pancreatitis the basis of a target organs lesion is membranodestruktivny process due to excess activity of lipids peroxidation processes and phospholipase systems which are registered not only in a blood plasma, but also in tissue structures of the studied organs — an intestine, a liver, kidneys (systemic distress damages of oxidative and phospholipase induced character) acts.

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Published

2015-07-09

Issue

Vol. 59 No. 2 (2015)

Section

Original research

How to Cite

[1]
2015. Systemic factors of acute pancreatitis advance. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 59, 2 (Jul. 2015), 46–50.

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