The effect of the biopolymer chondroitin sulfate on reparative regeneration of connective tissue

Authors

  • S. V. Belova Saratov Research Institute of Traumatology and Orthopedics, Saratov, Russian Federation
  • I. A. Norkin Saratov Research Institute of Traumatology and Orthopedics, Saratov, Russian Federation
  • D. M. Puchinyan Saratov Research Institute of Traumatology and Orthopedics, Saratov, Russian Federation

Keywords:

connective tissue, reparative regeneration, intra-articular introduction, experimental arthritis, chondroitin sulfate

Abstract

The research objective is a study of an intra-articular method of introduction of the preparation «mukosat» for stimulation of reparative regeneration of connective tissue of knee joints in rabbits with an experimental arthritis. It is ascertained that intra-articular introduction of chondroitin sulfate (the preparation «mukosat») acts as а stimulus for reparative regeneration of connective tissue thus showing up positive changes in the status of connective tissue elements of joints: decrease in glycosaminoglycan content in blood serum and normalization of the composition of glycosaminoglycan carbohydrate component. It probably depends on stimulation of biosynthesis of autologous normal glycosaminoglycans in tissues of animal knee joints.

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Published

2015-04-08

Issue

Vol. 59 No. 1 (2015)

Section

Original research

How to Cite

[1]
2015. The effect of the biopolymer chondroitin sulfate on reparative regeneration of connective tissue. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 59, 1 (Apr. 2015), 76–79.

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