Pathophysiological aspects of changing of metabolism in patients with severe mechanical trauma

Authors

  • A. V. Selivanova City Clinical Hospital of Botkin, Moscow, Russia, 2-St Botkinsky proezd, 5, tel.: 8-495-945-0045; Institute of General pathology and pathophysiology RAMN, Moscow, the Baltic Street, 8, tel.: 8-499-151-1756)
  • Yu. V. Marchenkov City Clinical Hospital of Botkin, Moscow, Russia, 2-St Botkinsky proezd, 5, tel.: 8-495-945-0045; Institute of General Reanimatology of Negovskogo, Moscow, Petrovka street 25/2, tel.: 8-495-694-27-08

Keywords:

critical condition, polytrauma, syndrome of hypermetabolism-hypercatabolism

Abstract

The review presents contemporary look at the problem of the cascade of pathophysiological reactions in patients with severe mechanical trauma. In the article described in detail changes hormonal and metabolic parameters in this category patients. In severe cases this leads to the development the syndrome of hypermetabolism-hypercatabolizm. Patients with this syndrome have a resistance to the introduction of exogenous nutrients. Syndrome of hypermetabolism-hypercatabolizm play a leading role in the pathogenesis of critical condition, it determines the outcome of the disease in general. The article studied in detail the pathogenesis of the processes occurring in critically ill patients, taking into account the pathogenetic mechanism of development are possible solutions to this complex issue.

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Published

2014-09-12

Issue

Vol. 58 No. 3 (2014)

Section

Reviews

How to Cite

[1]
2014. Pathophysiological aspects of changing of metabolism in patients with severe mechanical trauma. Patologicheskaya Fiziologiya i Eksperimental’naya Terapiya (Pathological physiology and experimental therapy). 58, 3 (Sep. 2014), 88–92.